Allopurinol

Snap Intermediates
Products


Allopurinol

Molecular Formula: C5H4N4O
CAS Number: 315-30-0
Molecular Weight: 136.11
Synonyms:
TIMTEC-BB SBB004202;ISOPURINOL;LABOTEST-BB LT00244764;HPP;1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-OL;AKOS BBS-00005290;ALLPURINOL;AKOS BBS-00002073
Product Specifications:
mp >300 degreesC(lit.)
storage temp.: Room temperature.
Water Solubility: 0.35 g/L (25 degrees C)
Merck 279
Additional Information:
Chemical Properties:
--------------------
White to Off-White Solid

Usage:
-----------
Xanthine oxidase inhibitor; decreases uric acid production. Used in treatment of hyperuricemia and chronic gout. Antiurolithic

General Description:
--------------------
Odorless tasteless white microcrystalline powder.

Air & Water Reactions:
-----------------------
Insoluble in water.

Reactivity Profile:
-------------------
Allopurinol is an aminoalcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Allopurinol darkens above 572° F, and at an indefinite high temperature, Allopurinol chars and decomposes. At 221° F, maximum stability occurs at pH 3.1- 3.4. Allopurinol decomposes in acidic and basic solutions.

Fire Hazard:
-------------
Flash point data for Allopurinol are not available; however, Allopurinol is probably combustible.