storage temp. −20°C
solubility H2O: 0.7 mg/mL
Stability: Stable. Incompatible with strong oxidizing agents.
Chemical Properties white to light yellow crystal powder
Usage Orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral
Biological Activity Antiviral agent, active against herpes simplex viruses HSV-1 and HSV-2 (EC 50 values are 0.85 and 0.86 μ M respectively). Interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate. Induces apoptosis in cells transfected with HSV-TK (suicidal gene therapy).